MIDDAS-M: Motif-Independent De Novo Detection of Secondary Metabolite Gene Clusters through the Integration of Genome Sequencing and Transcriptome Data

Many bioactive natural products are produced as “secondary metabolites” by plants, bacteria, and fungi. During the middle of the 20th century, several secondary metabolites from fungi revolutionized the pharmaceutical industry, for example, penicillin, lovastatin, and cyclosporine. They are generall...

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Detalles Bibliográficos
Autores principales: Umemura, Myco, Koike, Hideaki, Nagano, Nozomi, Ishii, Tomoko, Kawano, Jin, Yamane, Noriko, Kozone, Ikuko, Horimoto, Katsuhisa, Shin-ya, Kazuo, Asai, Kiyoshi, Yu, Jiujiang, Bennett, Joan W., Machida, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877130/
https://www.ncbi.nlm.nih.gov/pubmed/24391870
http://dx.doi.org/10.1371/journal.pone.0084028

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