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Increased Skeletal Muscle 11βHSD1 mRNA Is Associated with Lower Muscle Strength in Ageing
BACKGROUND: Sarcopenia, the loss of muscle mass and function with age, is associated with increased morbidity and mortality. Current understanding of the underlying mechanisms is limited. Glucocorticoids (GC) in excess cause muscle weakness and atrophy. We hypothesized that GC may contribute to sarc...
Autores principales: | Kilgour, Alixe H. M., Gallagher, Iain J., MacLullich, Alasdair M. J., Andrew, Ruth, Gray, Calum D., Hyde, Philippa, Wackerhage, Henning, Husi, Holger, Ross, James A., Starr, John M., Chapman, Karen E., Fearon, Kenneth C. H., Walker, Brian R., Greig, Carolyn A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877148/ https://www.ncbi.nlm.nih.gov/pubmed/24391882 http://dx.doi.org/10.1371/journal.pone.0084057 |
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