Increased Skeletal Muscle 11βHSD1 mRNA Is Associated with Lower Muscle Strength in Ageing

BACKGROUND: Sarcopenia, the loss of muscle mass and function with age, is associated with increased morbidity and mortality. Current understanding of the underlying mechanisms is limited. Glucocorticoids (GC) in excess cause muscle weakness and atrophy. We hypothesized that GC may contribute to sarc...

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Detalles Bibliográficos
Autores principales: Kilgour, Alixe H. M., Gallagher, Iain J., MacLullich, Alasdair M. J., Andrew, Ruth, Gray, Calum D., Hyde, Philippa, Wackerhage, Henning, Husi, Holger, Ross, James A., Starr, John M., Chapman, Karen E., Fearon, Kenneth C. H., Walker, Brian R., Greig, Carolyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877148/
https://www.ncbi.nlm.nih.gov/pubmed/24391882
http://dx.doi.org/10.1371/journal.pone.0084057

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