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Mrassf1a-Pap, a Novel Methylation-Based Assay for the Detection of Cell-Free Fetal DNA in Maternal Plasma

OBJECTIVES: RASSF1A has been described to be differentially methylated between fetal and maternal DNA and can therefore be used as a universal sex-independent marker to confirm the presence of fetal sequences in maternal plasma. However, this requires highly sensitive methods. We have previously sho...

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Detalles Bibliográficos
Autores principales:	van den Oever, Jessica M. E., Balkassmi, Sahila, Segboer, Tim, Verweij, E. Joanne, van der Velden, Pieter A., Oepkes, Dick, Bakker, Egbert, Boon, Elles M. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877162/ https://www.ncbi.nlm.nih.gov/pubmed/24391879 http://dx.doi.org/10.1371/journal.pone.0084051

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