Myxoma Virus Oncolytic Efficiency Can Be Enhanced Through Chemical or Genetic Disruption of the Actin Cytoskeleton

Myxoma virus (MYXV) is one of many animal viruses that exhibit oncolytic properties in transformed human cells. Compared to orthopoxviruses like vaccinia (VACV), MYXV spreads inefficiently, which could compromise its use in treating tumors and their associated metastases. The VACV F11 protein promot...

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Detalles Bibliográficos
Autores principales: Irwin, Chad R., Favis, Nicole A., Agopsowicz, Kate C., Hitt, Mary M., Evans, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877188/
https://www.ncbi.nlm.nih.gov/pubmed/24391902
http://dx.doi.org/10.1371/journal.pone.0084134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877188/
https://www.ncbi.nlm.nih.gov/pubmed/24391902
http://dx.doi.org/10.1371/journal.pone.0084134

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