Cargando…

Myxoma Virus Oncolytic Efficiency Can Be Enhanced Through Chemical or Genetic Disruption of the Actin Cytoskeleton

Myxoma virus (MYXV) is one of many animal viruses that exhibit oncolytic properties in transformed human cells. Compared to orthopoxviruses like vaccinia (VACV), MYXV spreads inefficiently, which could compromise its use in treating tumors and their associated metastases. The VACV F11 protein promot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Irwin, Chad R., Favis, Nicole A., Agopsowicz, Kate C., Hitt, Mary M., Evans, David H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877188/ https://www.ncbi.nlm.nih.gov/pubmed/24391902 http://dx.doi.org/10.1371/journal.pone.0084134

Ejemplares similares

Targeting Nucleotide Biosynthesis: A Strategy for Improving the Oncolytic Potential of DNA Viruses
por: Irwin, Chad R., et al.
Publicado: (2017)

Improved oncolytic activity of a reovirus mutant that displays enhanced virus spread due to reduced cell attachment
por: Cristi, Francisca, et al.
Publicado: (2023)

Deletion of F4L (ribonucleotide reductase) in vaccinia virus produces a selective oncolytic virus and promotes anti‐tumor immunity with superior safety in bladder cancer models
por: Potts, Kyle G, et al.
Publicado: (2017)

Radiation-Induced Cellular Senescence Reduces Susceptibility of Glioblastoma Cells to Oncolytic Vaccinia Virus
por: Storozynsky, Quinn T., et al.
Publicado: (2023)

Oncolytic Virotherapy with Myxoma Virus
por: Rahman, Masmudur M., et al.
Publicado: (2020)

Induction of chondrogenesis in limb mesenchymal cultures by disruption of the actin cytoskeleton
Publicado: (1984)

Breast Cancer Selective Disruption of Actin Cytoskeleton by Diallyl Trisulfide
por: Hahm, Eun-Ryeong, et al.
Publicado: (2022)

Disrupting actin filaments enhances glucose-stimulated insulin secretion independent of the cortical actin cytoskeleton
por: Polino, Alexander J., et al.
Publicado: (2023)

Disrupting actin filaments enhances glucose-stimulated insulin secretion independent of the cortical actin cytoskeleton
por: Polino, Alexander J., et al.
Publicado: (2023)

Fix Your Membrane Receptor Imaging: Actin Cytoskeleton and CD4 Membrane Organization Disruption by Chemical Fixation
por: Pereira, Pedro M., et al.
Publicado: (2019)

Disruption of the actin cytoskeleton after microinjection of proteolytic fragments of alpha-actinin
Publicado: (1991)

Metabolic signatures associated with oncolytic myxoma viral infections
por: Mahar, Rohit, et al.
Publicado: (2022)

Tunneling nanotubes and actin cytoskeleton dynamics in glaucoma
por: Keller, Kate E.
Publicado: (2020)

Actin cytoskeleton in angiogenesis
por: Yadunandanan Nair, Nidhi, et al.
Publicado: (2022)

Baculovirus Actin Rearrangement-Inducing Factor 1 Can Remodel the Mammalian Actin Cytoskeleton
por: Steffen, Anika, et al.
Publicado: (2023)

Growth inhibition associated with disruption of the actin cytoskeleton by Latrunculin A in rhabdomyosarcoma cells
por: Würtemberger, Julia, et al.
Publicado: (2020)

Oncolytic Viruses in the Treatment of Bladder Cancer
por: Potts, Kyle G., et al.
Publicado: (2012)

Safety of an Oncolytic Myxoma Virus in Dogs with Soft Tissue Sarcoma
por: MacNeill, Amy L., et al.
Publicado: (2018)

Impact of Induced Syncytia Formation on the Oncolytic Potential of Myxoma Virus
por: Burton, Chase, et al.
Publicado: (2019)

Regulation of the Postsynaptic Compartment of Excitatory Synapses by the Actin Cytoskeleton in Health and Its Disruption in Disease
por: Stefen, Holly, et al.
Publicado: (2016)

A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis
por: Gill, Martin R., et al.
Publicado: (2022)

Dynamic reorganization of the actin cytoskeleton
por: Letort, Gaëlle, et al.
Publicado: (2015)

Regulation of the Actin Cytoskeleton in Podocytes
por: Blaine, Judith, et al.
Publicado: (2020)

Genetic Modifications That Expand Oncolytic Virus Potency
por: Cristi, Francisca, et al.
Publicado: (2022)

Oncolytic myxoma virus synergizes with standard of care for treatment of glioblastoma multiforme
por: Burton, Chase, et al.
Publicado: (2018)

TNF blockade enhances the efficacy of myxoma virus-based oncolytic virotherapy
por: Valenzuela-Cardenas, Miriam, et al.
Publicado: (2022)

Autologous Transplantation Using Donor Leukocytes Loaded Ex Vivo with Oncolytic Myxoma Virus Can Eliminate Residual Multiple Myeloma
por: Villa, Nancy.Y., et al.
Publicado: (2020)

HopW1 from Pseudomonas syringae Disrupts the Actin Cytoskeleton to Promote Virulence in Arabidopsis
por: Kang, Yongsung, et al.
Publicado: (2014)

F5-peptide induces aspermatogenesis by disrupting organization of actin- and microtubule-based cytoskeletons in the testis
por: Gao, Ying, et al.
Publicado: (2016)

Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar
por: Su, Linlin, et al.
Publicado: (2016)

Disrupting the cortical actin cytoskeleton points to two distinct mechanisms of yeast [PSI(+)] prion formation
por: Speldewinde, Shaun H., et al.
Publicado: (2017)

Actin Cytoskeleton Regulates Hippo Signaling
por: Reddy, Pradeep, et al.
Publicado: (2013)

Regulation and integrated functions of the actin cytoskeleton
por: Charras, Guillaume, et al.
Publicado: (2016)

Regulation of Mitochondrial Function by the Actin Cytoskeleton
por: Illescas, María, et al.
Publicado: (2021)

Dynamics of the Actin Cytoskeleton at Adhesion Complexes
por: Cronin, Nicholas M., et al.
Publicado: (2021)

Actin-Myosin Cytoskeleton Regulation and Function
por: Olson, Michael F.
Publicado: (2022)

Apoptosis in platelets is independent of the actin cytoskeleton
por: De Silva, Enoli, et al.
Publicado: (2022)

TRPV2 interacts with actin and reorganizes submembranous actin cytoskeleton
por: Yadav, Manoj, et al.
Publicado: (2020)

Actin-Associated Proteins and Small Molecules Targeting the Actin Cytoskeleton
por: Gao, Jing, et al.
Publicado: (2022)

Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton
por: Kumar, Vinod, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lh8h5hd3crmjdut44rt57u9v2s