Identification of the Third Binding Site of Arsenic in Human Arsenic (III) Methyltransferase

Arsenic (III) methyltransferase (AS3MT) catalyzes the process of arsenic methylation. Each arsenite (iAs(3+)) binds to three cysteine residues, methylarsenite (MMA(3+)) binds to two, and dimethylarsenite (DMA(3+)) binds to one. However, only two As-binding sites (Cys156 and Cys206) have been confirm...

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Detalles Bibliográficos
Autores principales: Li, Xiangli, Geng, Zhirong, Chang, Jiayin, Wang, Shuping, Song, Xiaoli, Hu, Xin, Wang, Zhilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877260/
https://www.ncbi.nlm.nih.gov/pubmed/24391919
http://dx.doi.org/10.1371/journal.pone.0084231

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