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Screening Fluorescent Voltage Indicators with Spontaneously Spiking HEK Cells

Development of improved fluorescent voltage indicators is a key challenge in neuroscience, but progress has been hampered by the low throughput of patch-clamp characterization. We introduce a line of non-fluorescent HEK cells that stably express Na(V) 1.3 and K(IR) 2.1 and generate spontaneous elect...

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Detalles Bibliográficos
Autores principales:	Park, Jeehae, Werley, Christopher A., Venkatachalam, Veena, Kralj, Joel M., Dib-Hajj, Sulayman D., Waxman, Stephen G., Cohen, Adam E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877367/ https://www.ncbi.nlm.nih.gov/pubmed/24391999 http://dx.doi.org/10.1371/journal.pone.0085221

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