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Joint Effect of Multiple Common SNPs Predicts Melanoma Susceptibility

Single genetic variants discovered so far have been only weakly associated with melanoma. This study aims to use multiple single nucleotide polymorphisms (SNPs) jointly to obtain a larger genetic effect and to improve the predictive value of a conventional phenotypic model. We analyzed 11 SNPs that...

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Detalles Bibliográficos
Autores principales: Fang, Shenying, Han, Jiali, Zhang, Mingfeng, Wang, Li-e, Wei, Qingyi, Amos, Christopher I., Lee, Jeffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877376/
https://www.ncbi.nlm.nih.gov/pubmed/24392023
http://dx.doi.org/10.1371/journal.pone.0085642

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