Cargando…
Grave's disease with transverse and sigmoid sinus thrombosis needing surgical intervention
Thrombosis of venous sinuses associated with thyrotoxicosis is rare, and isolated transverse and sigmoid sinus thrombosis is rarer and reported only once previously. We present a case of Graves disease, who suffered unilateral sigmoid and transverse sinus thrombosis with intracranial hemorrhage. A 4...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877505/ https://www.ncbi.nlm.nih.gov/pubmed/24403961 http://dx.doi.org/10.4103/1793-5482.121690 |
_version_ | 1782297662989533184 |
---|---|
author | Srikant, Banumathy Balasubramaniam, Srikant |
author_facet | Srikant, Banumathy Balasubramaniam, Srikant |
author_sort | Srikant, Banumathy |
collection | PubMed |
description | Thrombosis of venous sinuses associated with thyrotoxicosis is rare, and isolated transverse and sigmoid sinus thrombosis is rarer and reported only once previously. We present a case of Graves disease, who suffered unilateral sigmoid and transverse sinus thrombosis with intracranial hemorrhage. A 42-year-old female, a diagnosed case of Graves disease, presented to us with headache, drowsiness, and hemiparesis. Computed Tomography revealed a large right temporo-parieto-occipital venous infarct. The patient needed surgical intervention in the form of decompressive craniotomy following which she improved, and on follow-up is having no deficits. Thrombophilia profile showed a low Protein S and Anti thrombin III (AT III) levels. Deranged thrombophilia profile in combination with the hypercoagulable state in thyrotoxicosis, most likely precipitated the thrombotic event. Timely surgical intervention can be offered in selective cases with a good clinical outcome. |
format | Online Article Text |
id | pubmed-3877505 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38775052014-01-08 Grave's disease with transverse and sigmoid sinus thrombosis needing surgical intervention Srikant, Banumathy Balasubramaniam, Srikant Asian J Neurosurg Case Report Thrombosis of venous sinuses associated with thyrotoxicosis is rare, and isolated transverse and sigmoid sinus thrombosis is rarer and reported only once previously. We present a case of Graves disease, who suffered unilateral sigmoid and transverse sinus thrombosis with intracranial hemorrhage. A 42-year-old female, a diagnosed case of Graves disease, presented to us with headache, drowsiness, and hemiparesis. Computed Tomography revealed a large right temporo-parieto-occipital venous infarct. The patient needed surgical intervention in the form of decompressive craniotomy following which she improved, and on follow-up is having no deficits. Thrombophilia profile showed a low Protein S and Anti thrombin III (AT III) levels. Deranged thrombophilia profile in combination with the hypercoagulable state in thyrotoxicosis, most likely precipitated the thrombotic event. Timely surgical intervention can be offered in selective cases with a good clinical outcome. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3877505/ /pubmed/24403961 http://dx.doi.org/10.4103/1793-5482.121690 Text en Copyright: © Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Srikant, Banumathy Balasubramaniam, Srikant Grave's disease with transverse and sigmoid sinus thrombosis needing surgical intervention |
title | Grave's disease with transverse and sigmoid sinus thrombosis needing surgical intervention |
title_full | Grave's disease with transverse and sigmoid sinus thrombosis needing surgical intervention |
title_fullStr | Grave's disease with transverse and sigmoid sinus thrombosis needing surgical intervention |
title_full_unstemmed | Grave's disease with transverse and sigmoid sinus thrombosis needing surgical intervention |
title_short | Grave's disease with transverse and sigmoid sinus thrombosis needing surgical intervention |
title_sort | grave's disease with transverse and sigmoid sinus thrombosis needing surgical intervention |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877505/ https://www.ncbi.nlm.nih.gov/pubmed/24403961 http://dx.doi.org/10.4103/1793-5482.121690 |
work_keys_str_mv | AT srikantbanumathy gravesdiseasewithtransverseandsigmoidsinusthrombosisneedingsurgicalintervention AT balasubramaniamsrikant gravesdiseasewithtransverseandsigmoidsinusthrombosisneedingsurgicalintervention |