Triptolide induces apoptosis in human leukemia cells through caspase-3-mediated ROCK1 activation and MLC phosphorylation

The diterpene triepoxide triptolide is a major active component of Tripterygium wilfordii Hook F, a popular Chinese herbal medicine with the potential to treat hematologic malignancies. In this study, we investigated the roles of triptolide in apoptosis and cell signaling events in human leukemia ce...

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Detalles Bibliográficos
Autores principales: Liu, L, Li, G, Li, Q, Jin, Z, Zhang, L, Zhou, J, Hu, X, Zhou, T, Chen, J, Gao, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877542/
https://www.ncbi.nlm.nih.gov/pubmed/24309928
http://dx.doi.org/10.1038/cddis.2013.469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877542/
https://www.ncbi.nlm.nih.gov/pubmed/24309928
http://dx.doi.org/10.1038/cddis.2013.469

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