The ROS/JNK/ATF2 pathway mediates selenite-induced leukemia NB4 cell cycle arrest and apoptosis in vitro and in vivo

It has previously been shown that selenite can act as an antitumor agent and inhibit cancer cell growth, although the mechanism responsible for this effect is not well understood. In this study, we have shown that selenite can induce cell cycle arrest and apoptosis in NB4 cells. Selenite treatment o...

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Detalles Bibliográficos
Autores principales: An, J J, Shi, K J, Wei, W, Hua, F Y, Ci, Y L, Jiang, Q, Li, F, Wu, P, Hui, K Y, Yang, Y, Xu, C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877548/
https://www.ncbi.nlm.nih.gov/pubmed/24357804
http://dx.doi.org/10.1038/cddis.2013.475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877548/
https://www.ncbi.nlm.nih.gov/pubmed/24357804
http://dx.doi.org/10.1038/cddis.2013.475

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