Mycobacterial HBHA induces endoplasmic reticulum stress-mediated apoptosis through the generation of reactive oxygen species and cytosolic Ca(2+) in murine macrophage RAW 264.7 cells

Mycobacterial heparin-binding haemagglutinin antigen (HBHA) is a virulence factor that induces apoptosis of macrophages. Endoplasmic reticulum (ER) stress-mediated apoptosis is an important regulatory response that can be utilised to study the pathogenesis of tuberculosis. In the present study, HBHA...

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Detalles Bibliográficos
Autores principales: Choi, J-A, Lim, Y-J, Cho, S-N, Lee, J-H, Jeong, J A, Kim, E J, Park, J B, Kim, S H, Park, H S, Kim, H-J, Song, C-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877560/
https://www.ncbi.nlm.nih.gov/pubmed/24336077
http://dx.doi.org/10.1038/cddis.2013.489

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