Integrating protein-protein interaction networks with phenotypes reveals signs of interactions

A major objective of systems biology is to organize molecular interactions as networks and to characterize information-flow within networks. We describe a computational framework to integrate protein-protein interaction (PPI) networks and genetic screens to predict the “signs” of interactions (i.e....

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Detalles Bibliográficos
Autores principales: Vinayagam, Arunachalam, Zirin, Jonathan, Roesel, Charles, Hu, Yanhui, Yilmazel, Bahar, Samsonova, Anastasia A., Neumüller, Ralph A., Mohr, Stephanie E., Perrimon, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877743/
https://www.ncbi.nlm.nih.gov/pubmed/24240319
http://dx.doi.org/10.1038/nmeth.2733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877743/
https://www.ncbi.nlm.nih.gov/pubmed/24240319
http://dx.doi.org/10.1038/nmeth.2733

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