Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway

The self-renewal versus differentiation choice of Drosophila and mammalian neural stem cells (NSCs) requires Notch (N) signaling. How N regulates NSC behavior is not well understood. Here we show that canonical N signaling cooperates with a noncanonical N signaling pathway to mediate N-directed NSC...

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Detalles Bibliográficos
Autores principales: Lee, Kyu-Sun, Wu, Zhihao, Song, Yan, Mitra, Siddhartha S., Feroze, Abdullah H., Cheshier, Samuel H., Lu, Bingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877754/
https://www.ncbi.nlm.nih.gov/pubmed/24352421
http://dx.doi.org/10.1101/gad.225169.113

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