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Learning improvement after PI3K activation correlates with de novo formation of functional small spines
PI3K activation promotes the formation of synaptic contacts and dendritic spines, morphological features of glutamatergic synapses that are commonly known to be related to learning processes. In this report, we show that in vivo administration of a peptide that activates the PI3K signaling pathway i...
Autores principales: | Enriquez-Barreto, Lilian, Cuesto, Germán, Dominguez-Iturza, Nuria, Gavilán, Elena, Ruano, Diego, Sandi, Carmen, Fernández-Ruiz, Antonio, Martín-Vázquez, Gonzalo, Herreras, Oscar, Morales, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877779/ https://www.ncbi.nlm.nih.gov/pubmed/24427113 http://dx.doi.org/10.3389/fnmol.2013.00054 |
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