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Optimization and control in bacterial Lag phase

The lag phase of bacterial growth is important from a medical and food safety perspective, but difficult to study due to the low density and metabolic rate of cells. A new study by Alon and colleagues reveals that the gene expression program during early lag phase prioritizes carbon source utilizati...

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Detalles Bibliográficos
Autores principales: Schultz, Daniel, Kishony, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877865/
https://www.ncbi.nlm.nih.gov/pubmed/24377387
http://dx.doi.org/10.1186/1741-7007-11-120
Descripción
Sumario:The lag phase of bacterial growth is important from a medical and food safety perspective, but difficult to study due to the low density and metabolic rate of cells. A new study by Alon and colleagues reveals that the gene expression program during early lag phase prioritizes carbon source utilization enzymes over genes responsible for biomass accumulation. This cellular strategy ultimately maximizes growth, making the best long-term use of the new nutrient-rich environment. See research article: http://www.biomedcentral.com/1752-0509/7/136