The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home

We conducted a double-blind randomized controlled study of elderly individuals in a nursing home to investigate the effect of the consumption of jelly containing sea cucumber on their oral Candida load. The jelly contained a hydrolysate of the sea cucumber Stichopus japonicus, which contained triter...

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Autores principales: Yano, Akira, Abe, Akiko, Aizawa, Fumie, Yamada, Hidetoshi, Minami, Kentaro, Matsui, Miki, Kishi, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877898/
https://www.ncbi.nlm.nih.gov/pubmed/24335524
http://dx.doi.org/10.3390/md11124993
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author Yano, Akira
Abe, Akiko
Aizawa, Fumie
Yamada, Hidetoshi
Minami, Kentaro
Matsui, Miki
Kishi, Mitsuo
author_facet Yano, Akira
Abe, Akiko
Aizawa, Fumie
Yamada, Hidetoshi
Minami, Kentaro
Matsui, Miki
Kishi, Mitsuo
author_sort Yano, Akira
collection PubMed
description We conducted a double-blind randomized controlled study of elderly individuals in a nursing home to investigate the effect of the consumption of jelly containing sea cucumber on their oral Candida load. The jelly contained a hydrolysate of the sea cucumber Stichopus japonicus, which contained triterpene glycosides called holotoxins. The holotoxins worked as a fungicide, and their minimum inhibitory concentrations for Candida albicans were 7 µg/mL. Eight individuals in the nursing home took the sea cucumber jelly for a week and their oral Candida were counted before and after the intervention. Nine individuals took a control jelly without S. japonicus. The sea cucumber jelly showed inhibitory effects on the oral Candida. Thus, daily consumption of the S. japonicus jelly has the potential to reduce the oral Candida load in the elderly in nursing homes.
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spelling pubmed-38778982014-01-02 The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home Yano, Akira Abe, Akiko Aizawa, Fumie Yamada, Hidetoshi Minami, Kentaro Matsui, Miki Kishi, Mitsuo Mar Drugs Article We conducted a double-blind randomized controlled study of elderly individuals in a nursing home to investigate the effect of the consumption of jelly containing sea cucumber on their oral Candida load. The jelly contained a hydrolysate of the sea cucumber Stichopus japonicus, which contained triterpene glycosides called holotoxins. The holotoxins worked as a fungicide, and their minimum inhibitory concentrations for Candida albicans were 7 µg/mL. Eight individuals in the nursing home took the sea cucumber jelly for a week and their oral Candida were counted before and after the intervention. Nine individuals took a control jelly without S. japonicus. The sea cucumber jelly showed inhibitory effects on the oral Candida. Thus, daily consumption of the S. japonicus jelly has the potential to reduce the oral Candida load in the elderly in nursing homes. MDPI 2013-12-11 /pmc/articles/PMC3877898/ /pubmed/24335524 http://dx.doi.org/10.3390/md11124993 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Yano, Akira
Abe, Akiko
Aizawa, Fumie
Yamada, Hidetoshi
Minami, Kentaro
Matsui, Miki
Kishi, Mitsuo
The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home
title The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home
title_full The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home
title_fullStr The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home
title_full_unstemmed The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home
title_short The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home
title_sort effect of eating sea cucumber jelly on candida load in the oral cavity of elderly individuals in a nursing home
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877898/
https://www.ncbi.nlm.nih.gov/pubmed/24335524
http://dx.doi.org/10.3390/md11124993
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