Cargando…
Structural Aspects of GPCR-G Protein Coupling
G protein-coupled receptors (GPCRs) are membrane receptors; approximately 40% of drugs on the market target GPCRs. A precise understanding of the activation mechanism of GPCRs would facilitate the development of more effective and less toxic drugs. Heterotrimeric G proteins are important molecular s...
Autor principal: | Chung, Ka Young |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Toxicology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877993/ https://www.ncbi.nlm.nih.gov/pubmed/24386514 http://dx.doi.org/10.5487/TR.2013.29.3.149 |
Ejemplares similares
-
Coevolution underlies GPCR-G protein selectivity and functionality
por: Seo, Min Jae, et al.
Publicado: (2021) -
Variable G protein determinants of GPCR coupling selectivity
por: Okashah, Najeah, et al.
Publicado: (2019) -
Expanding the Concept of G Protein-Coupled Receptor (GPCR) Dimer Asymmetry towards GPCR-Interacting Proteins
por: Kamal, Maud, et al.
Publicado: (2011) -
Structure of the class D GPCR Ste2 dimer coupled to two G proteins
por: Velazhahan, Vaithish, et al.
Publicado: (2021) -
Common coupling map advances GPCR-G protein selectivity
por: Hauser, Alexander S, et al.
Publicado: (2022)