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Structural Aspects of GPCR-G Protein Coupling

G protein-coupled receptors (GPCRs) are membrane receptors; approximately 40% of drugs on the market target GPCRs. A precise understanding of the activation mechanism of GPCRs would facilitate the development of more effective and less toxic drugs. Heterotrimeric G proteins are important molecular s...

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Detalles Bibliográficos
Autor principal: Chung, Ka Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Toxicology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877993/
https://www.ncbi.nlm.nih.gov/pubmed/24386514
http://dx.doi.org/10.5487/TR.2013.29.3.149

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