Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?

A recent study investigated the therapeutic response of dogs afflicted by hip osteoarthritis when evaluating therapeutic modalities compared to a negative (placebo) control group. Authors suggested a placebo effect based on peak vertical force measurement. In addition, small effect size for each of...

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Detalles Bibliográficos
Autores principales: Moreau, Maxim, Lussier, Bertrand, Pelletier, Jean-Pierre, Troncy, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878098/
https://www.ncbi.nlm.nih.gov/pubmed/24359688
http://dx.doi.org/10.1186/1746-6148-9-260
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author Moreau, Maxim
Lussier, Bertrand
Pelletier, Jean-Pierre
Troncy, Eric
author_facet Moreau, Maxim
Lussier, Bertrand
Pelletier, Jean-Pierre
Troncy, Eric
author_sort Moreau, Maxim
collection PubMed
description A recent study investigated the therapeutic response of dogs afflicted by hip osteoarthritis when evaluating therapeutic modalities compared to a negative (placebo) control group. Authors suggested a placebo effect based on peak vertical force measurement. In addition, small effect size for each of the tested therapeutics as well as the extremely large sample size needed (>450) to discern therapeutic efficacy using force platform gait analysis were reported. We wish to express our concerns regarding the eligibility criteria used to select the studied cohort, the small effect size, and the placebo effect reported in force platform gait analysis.
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spelling pubmed-38780982014-01-03 Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis? Moreau, Maxim Lussier, Bertrand Pelletier, Jean-Pierre Troncy, Eric BMC Vet Res Correspondence A recent study investigated the therapeutic response of dogs afflicted by hip osteoarthritis when evaluating therapeutic modalities compared to a negative (placebo) control group. Authors suggested a placebo effect based on peak vertical force measurement. In addition, small effect size for each of the tested therapeutics as well as the extremely large sample size needed (>450) to discern therapeutic efficacy using force platform gait analysis were reported. We wish to express our concerns regarding the eligibility criteria used to select the studied cohort, the small effect size, and the placebo effect reported in force platform gait analysis. BioMed Central 2013-12-21 /pmc/articles/PMC3878098/ /pubmed/24359688 http://dx.doi.org/10.1186/1746-6148-9-260 Text en Copyright © 2013 Moreau et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Correspondence
Moreau, Maxim
Lussier, Bertrand
Pelletier, Jean-Pierre
Troncy, Eric
Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?
title Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?
title_full Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?
title_fullStr Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?
title_full_unstemmed Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?
title_short Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?
title_sort does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878098/
https://www.ncbi.nlm.nih.gov/pubmed/24359688
http://dx.doi.org/10.1186/1746-6148-9-260
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