Cargando…

Loss of IP(3) receptor function in neuropeptide secreting neurons leads to obesity in adult Drosophila

BACKGROUND: Intracellular calcium signaling regulates a variety of cellular and physiological processes. The inositol 1,4,5 trisphosphate receptor (IP(3)R) is a ligand gated calcium channel present on the membranes of endoplasmic reticular stores. In previous work we have shown that Drosophila mutan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Subramanian, Manivannan, Jayakumar, Siddharth, Richhariya, Shlesha, Hasan, Gaiti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878400/ https://www.ncbi.nlm.nih.gov/pubmed/24350669 http://dx.doi.org/10.1186/1471-2202-14-157

Ejemplares similares

dSTIM- and Ral/Exocyst-Mediated Synaptic Release from Pupal Dopaminergic Neurons Sustains Drosophila Flight
por: Richhariya, Shlesha, et al.
Publicado: (2018)

Drosophila larval to pupal switch under nutrient stress requires IP(3)R/Ca(2+) signalling in glutamatergic interneurons
por: Jayakumar, Siddharth, et al.
Publicado: (2016)

A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons
por: Richhariya, Shlesha, et al.
Publicado: (2017)

A Multicomponent Neuronal Response Encodes the Larval Decision to Pupariate upon Amino Acid Starvation
por: Jayakumar, Siddharth, et al.
Publicado: (2018)

Ral function in muscle is required for flight maintenance in Drosophila
por: Richhariya, Shlesha, et al.
Publicado: (2017)

Altered lipid homeostasis in Drosophila InsP(3) receptor mutants leads to obesity and hyperphagia
por: Subramanian, Manivannan, et al.
Publicado: (2013)

Spontaneous Ca(2+) Influx in Drosophila Pupal Neurons Is Modulated by IP(3)-Receptor Function and Influences Maturation of the Flight Circuit
por: Chakraborty, Sumita, et al.
Publicado: (2017)

Neuronal Calcium Signaling in Metabolic Regulation and Adaptation to Nutrient Stress
por: Jayakumar, Siddharth, et al.
Publicado: (2018)

ER-Ca(2+) sensor STIM regulates neuropeptides required for development under nutrient restriction in Drosophila
por: Megha,, et al.
Publicado: (2019)

A STIM dependent dopamine-neuropeptide axis maintains the larval drive to feed and grow in Drosophila
por: Kasturacharya, Nandashree, et al.
Publicado: (2023)

Control of protein translation by IP(3)R-mediated Ca(2+) release in Drosophila neuroendocrine cells
por: Megha, , et al.
Publicado: (2017)

Mutant IP(3) receptors attenuate store-operated Ca(2+) entry by destabilizing STIM–Orai interactions in Drosophila neurons
por: Chakraborty, Sumita, et al.
Publicado: (2016)

Dissecting neuron-specific functions of circadian genes using modified cell-specific CRISPR approaches
por: Richhariya, Shlesha, et al.
Publicado: (2023)

Modulation of flight and feeding behaviours requires presynaptic IP(3)Rs in dopaminergic neurons
por: Sharma, Anamika, et al.
Publicado: (2020)

IP(3)R-mediated Ca(2+) release regulates protein metabolism in Drosophila neuroendocrine cells: implications for development under nutrient stress
por: Megha,, et al.
Publicado: (2017)

A Genetic RNAi Screen for IP(3)/Ca(2+) Coupled GPCRs in Drosophila Identifies the PdfR as a Regulator of Insect Flight
por: Agrawal, Tarjani, et al.
Publicado: (2013)

The Enigma of Store-Operated Ca(2+)-Entry in Neurons: Answers from the Drosophila Flight Circuit
por: Hasan, Gaiti, et al.
Publicado: (2010)

FMRFa receptor stimulated Ca(2+) signals alter the activity of flight modulating central dopaminergic neurons in Drosophila melanogaster
por: Ravi, Preethi, et al.
Publicado: (2018)

Synaptic Activity in Serotonergic Neurons Is Required for Air-Puff Stimulated Flight in Drosophila melanogaster
por: Sadaf, Sufia, et al.
Publicado: (2012)

Dopamine and GPCR-mediated modulation of DN1 clock neurons gates the circadian timing of sleep
por: Schlichting, Matthias, et al.
Publicado: (2022)

Deficits Associated With Loss of STIM1 in Purkinje Neurons Including Motor Coordination Can Be Rescued by Loss of Septin 7
por: Dhanya, Sreeja Kumari, et al.
Publicado: (2021)

Substrates for Neuronal Cotransmission With Neuropeptides and Small Molecule Neurotransmitters in Drosophila
por: Nässel, Dick R.
Publicado: (2018)

Neuropeptide S- and Neuropeptide S receptor-expressing neuron populations in the human pons
por: Adori, Csaba, et al.
Publicado: (2015)

Inositol 1,4,5- Trisphosphate Receptor Function in Drosophila Insulin Producing Cells
por: Agrawal, Neha, et al.
Publicado: (2009)

The prominin-like Gene Expressed in a Subset of Dopaminergic Neurons Regulates Locomotion in Drosophila
por: Ryu, Tae Hoon, et al.
Publicado: (2022)

Molecular evolution of neuropeptides in the genus Drosophila
por: Wegener, Christian, et al.
Publicado: (2008)

Segment-specific generation of Drosophila Capability neuropeptide neurons by multi-faceted Hox cues
por: Suska, Anke, et al.
Publicado: (2011)

Neuropeptide F regulates courtship in Drosophila through a male-specific neuronal circuit
por: Liu, Weiwei, et al.
Publicado: (2019)

Role of the neuropeptide, bombesin, in bile secretion.
por: Cho, W. K.
Publicado: (1997)

RIC-7 Promotes Neuropeptide Secretion
por: Hao, Yingsong, et al.
Publicado: (2012)

Maturation of a central brain flight circuit in Drosophila requires Fz2/Ca(2+) signaling
por: Agrawal, Tarjani, et al.
Publicado: (2015)

Diet-Induced Obesity in Mice Overexpressing Neuropeptide Y in Noradrenergic Neurons
por: Ruohonen, Suvi T., et al.
Publicado: (2012)

The Neuropeptide PDF Is Crucial for Delaying the Phase of Drosophila’s Evening Neurons Under Long Zeitgeber Periods
por: Vaze, Koustubh M., et al.
Publicado: (2021)

Patterns of Gene Expression in Drosophila InsP(3) Receptor Mutant Larvae Reveal a Role for InsP(3) Signaling in Carbohydrate and Energy Metabolism
por: Kumar, Satish, et al.
Publicado: (2011)

Loss of MAPK8IP3 Affects Endocytosis in Neurons
por: Snead, Amanda M., et al.
Publicado: (2022)

A neuron-in-capillary platform for facile collection and mass spectrometric characterization of a secreted neuropeptide
por: Lee, Chang Young, et al.
Publicado: (2016)

Clathrin heavy chain 22 contributes to the control of neuropeptide degradation and secretion during neuronal development
por: Nahorski, Michael S., et al.
Publicado: (2018)

Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons
por: Vähätalo, L H, et al.
Publicado: (2015)

RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides
por: Abruzzi, Katharine C., et al.
Publicado: (2017)

Two photon imaging of calcium responses in murine Purkinje neurons
por: Dhanya, Sreeja Kumari, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_psvkput1f142ijspoignfeahsd