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PIK3CA, HRAS and PTEN in human papillomavirus positive oropharyngeal squamous cell carcinoma
BACKGROUND: Recent genomic evidence suggests frequent phosphatidylinositide 3-kinase (PI3K) pathway activation in human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma. Mutations/amplification of the gene encoding p110α catalytic subunit of phosphoinositide 3-kinase (PIK3CA), los...
Autores principales: | Chiosea, Simion I, Grandis, Jennifer R, Lui, Vivian W Y, Diergaarde, Brenda, Maxwell, Jessica H, Ferris, Robert L, Kim, Seungwon W, Luvison, Alyssa, Miller, Megan, Nikiforova, Marina N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878565/ https://www.ncbi.nlm.nih.gov/pubmed/24341335 http://dx.doi.org/10.1186/1471-2407-13-602 |
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