Cargando…
Involvement of the N-methyl-d-aspartate receptor GluN2D subunit in phencyclidine-induced motor impairment, gene expression, and increased Fos immunoreactivity
BACKGROUND: Noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonists evoke a behavioral and neurobiological syndrome in experimental animals. We previously reported that phencyclidine (PCP), an NMDA receptor antagonist, increased locomotor activity in wildtype (WT) mice but not GluN2D subunit...
Autores principales: | Yamamoto, Hideko, Kamegaya, Etsuko, Sawada, Wakako, Hasegawa, Ryota, Yamamoto, Toshifumi, Hagino, Yoko, Takamatsu, Yukio, Imai, Kazuhide, Koga, Hisashi, Mishina, Masayoshi, Ikeda, Kazutaka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878647/ https://www.ncbi.nlm.nih.gov/pubmed/24330819 http://dx.doi.org/10.1186/1756-6606-6-56 |
Ejemplares similares
-
Essential Role of NMDA Receptor Channel ε4 Subunit (GluN2D) in the Effects of Phencyclidine, but Not Methamphetamine
por: Hagino, Yoko, et al.
Publicado: (2010) -
Allosteric modulation of GluN1/GluN3 NMDA receptors by GluN1-selective competitive antagonists
por: Rouzbeh, Nirvan, et al.
Publicado: (2023) -
GluN2B and GluN2D NMDARs dominate synaptic responses in the adult spinal cord
por: Hildebrand, Michael E., et al.
Publicado: (2014) -
Unique Biology and Single-Channel Properties of GluN2A- and GluN2C-Containing Triheteromeric N-Methyl-D-Aspartate Receptors
por: Bhattacharya , Subhrajit, et al.
Publicado: (2018) -
GluN2A and GluN2B N-Methyl-D-Aspartate Receptor (NMDARs) Subunits: Their Roles and Therapeutic Antagonists in Neurological Diseases
por: Ladagu, Amany Digal, et al.
Publicado: (2023)