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The therapeutic efficacy of I(131)-PSCA-mAb in orthotopic mouse models of prostate cancer

BACKGROUND: Prostate stem cell antigen (PSCA) is upregulated in prostate cancer tissues. Here we aimed to study the therapeutic efficacy of a monoclonal antibody of PSCA-labeled I(131) (I(131)-PSCA-mAb) in orthotopic mouse models of prostate cancer. METHODS: The proliferation, apoptosis and invasion...

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Detalles Bibliográficos
Autores principales: Yu, Shengqiang, Feng, Fan, Wang, Ke, Men, Changping, Lin, Chunhua, Liu, Qingzuo, Yang, Diandong, Gao, Zhenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878678/
https://www.ncbi.nlm.nih.gov/pubmed/24330823
http://dx.doi.org/10.1186/2047-783X-18-56