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Loss of PINK1 enhances neurodegeneration in a mouse model of Parkinson's disease triggered by mitochondrial stress()

Parkinson's disease (PD) shows a complex etiology, where both genetic and environmental factors contribute to initiation and advance of pathology. Mitochondrial dysfunction and mutation of genes implicated in mitochondria quality control are recognized contributors to etiopathology and progress...

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Detalles Bibliográficos
Autores principales: Moisoi, Nicoleta, Fedele, Valentina, Edwards, Jennifer, Martins, L. Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878764/
https://www.ncbi.nlm.nih.gov/pubmed/24161480
http://dx.doi.org/10.1016/j.neuropharm.2013.10.009