Cargando…
Loss of PINK1 enhances neurodegeneration in a mouse model of Parkinson's disease triggered by mitochondrial stress()
Parkinson's disease (PD) shows a complex etiology, where both genetic and environmental factors contribute to initiation and advance of pathology. Mitochondrial dysfunction and mutation of genes implicated in mitochondria quality control are recognized contributors to etiopathology and progress...
Autores principales: | Moisoi, Nicoleta, Fedele, Valentina, Edwards, Jennifer, Martins, L. Miguel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878764/ https://www.ncbi.nlm.nih.gov/pubmed/24161480 http://dx.doi.org/10.1016/j.neuropharm.2013.10.009 |
Ejemplares similares
-
Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson's disease
por: Celardo, I, et al.
Publicado: (2016) -
The dysregulated Pink1(-) Drosophila mitochondrial proteome is partially corrected with exercise
por: Ebanks, Brad, et al.
Publicado: (2021) -
Intracellular and Intercellular Signalling Mechanisms following DNA Damage Are Modulated By PINK1
por: Temelie, Mihaela, et al.
Publicado: (2018) -
Pink1/Parkin link inflammation, mitochondrial stress, and neurodegeneration
por: Newman, Laura E., et al.
Publicado: (2018) -
PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis
por: Yang, Weili, et al.
Publicado: (2021)