Genomic amplification and high expression of EGFR are key targetable oncogenic events in malignant peripheral nerve sheath tumor

BACKGROUND: The dismal outcome of malignant peripheral nerve sheath tumor (MPNST) highlights the necessity of finding new therapeutic methods to benefit patients with this aggressive sarcoma. Our purpose was to investigate epidermal growth factor receptor (EGFR) as a potential therapeutic target in...

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Detalles Bibliográficos
Autores principales: Du, Xiaoling, Yang, Jilong, Ylipää, Antti, Zhu, Ze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878771/
https://www.ncbi.nlm.nih.gov/pubmed/24341609
http://dx.doi.org/10.1186/1756-8722-6-93

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