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Cathepsin K inhibitors increase distal femoral bone mineral density in rapidly growing rabbits

BACKGROUND: Selective and reversible inhibitors of human Cathepsin K (CatK), including odanacatib (ODN), have been developed as potential therapeutics for the treatment of osteoporosis. Inhibitors of human CatK show significantly less potency for the rodent enzymes compared with that for the human o...

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Detalles Bibliográficos
Autores principales:	Pennypacker, Brenda L, Oballa, Renata M, Levesque, Sonia, Kimmel, Donald B, Duong, Le T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878918/ https://www.ncbi.nlm.nih.gov/pubmed/24321244 http://dx.doi.org/10.1186/1471-2474-14-344

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