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CD8(+) T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants

BACKGROUND: Elite Controllers or Suppressors (ES) are HIV-1 positive individuals who maintain plasma viral loads below the limit of detection of standard clinical assays without antiretroviral therapy. Multiple lines of evidence suggest that the control of viral replication in these patients is due...

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Detalles Bibliográficos
Autores principales: Pohlmeyer, Christopher W, Buckheit, Robert W, Siliciano, Robert F, Blankson, Joel N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878989/
https://www.ncbi.nlm.nih.gov/pubmed/24330837
http://dx.doi.org/10.1186/1742-4690-10-152