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Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma

BACKGROUND: The chemokine receptor CCR7 mediates lymphoid dissemination of many cancers, including lymphomas and epithelial carcinomas, thus representing an attractive therapeutic target. Previous results have highlighted the potential of the anti-CCR7 monoclonal antibodies to inhibit migration in t...

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Detalles Bibliográficos
Autores principales: Somovilla-Crespo, Beatriz, Alfonso-Pérez, Manuel, Cuesta-Mateos, Carlos, Carballo-de Dios, Cristina, Beltrán, Amada E, Terrón, Fernando, Pérez-Villar, Juan J, Gamallo-Amat, Carlos, Pérez-Chacón, Gema, Fernández-Ruiz, Elena, Zapata, Juan M, Muñoz-Calleja, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879031/
https://www.ncbi.nlm.nih.gov/pubmed/24305507
http://dx.doi.org/10.1186/1756-8722-6-89

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