Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles

BACKGROUND: Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) that associate with clinical phenotypes, but these SNPs usually explain just a small part of the heritability and have relatively modest effect sizes. In contrast, SNPs that associat...

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Detalles Bibliográficos
Autores principales: Dharuri, Harish, Henneman, Peter, Demirkan, Ayse, van Klinken, Jan Bert, Mook-Kanamori, Dennis Owen, Wang-Sattler, Rui, Gieger, Christian, Adamski, Jerzy, Hettne, Kristina, Roos, Marco, Suhre, Karsten, Van Duijn, Cornelia M, van Dijk, Ko Willems, 't Hoen, Peter AC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879060/
https://www.ncbi.nlm.nih.gov/pubmed/24320595
http://dx.doi.org/10.1186/1471-2164-14-865

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