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wKinMut: An integrated tool for the analysis and interpretation of mutations in human protein kinases

BACKGROUND: Protein kinases are involved in relevant physiological functions and a broad number of mutations in this superfamily have been reported in the literature to affect protein function and stability. Unfortunately, the exploration of the consequences on the phenotypes of each individual muta...

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Detalles Bibliográficos
Autores principales: Izarzugaza, Jose MG, Vazquez, Miguel, del Pozo, Angela, Valencia, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879071/
https://www.ncbi.nlm.nih.gov/pubmed/24289158
http://dx.doi.org/10.1186/1471-2105-14-345