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Concomitant occurrence of EGFR (epidermal growth factor receptor) and KRAS (V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog) mutations in an ALK (anaplastic lymphoma kinase)-positive lung adenocarcinoma patient with acquired resistance to crizotinib: a case report

BACKGROUND: Anaplastic lymphoma kinase-positive non-small cell lung carcinoma patients are generally highly responsive to the dual anaplastic lymphoma kinase and MET tyrosine kinase inhibitor crizotinib. However, they eventually acquire resistance to this drug, preventing the anaplastic lymphoma kin...

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Detalles Bibliográficos
Autores principales:	Rossing, Henrik H, Grauslund, Morten, Urbanska, Edyta M, Melchior, Linea C, Rask, Charlotte K, Costa, Junia C, Skov, Birgit G, Sørensen, Jens Benn, Santoni-Rugiu, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879082/ https://www.ncbi.nlm.nih.gov/pubmed/24279718 http://dx.doi.org/10.1186/1756-0500-6-489

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