Cargando…
PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit
Entry into mitosis is triggered by activation of Cdk1 and inactivation of its counteracting phosphatase PP2A/B55. Greatwall kinase inactivates PP2A/B55 via its substrates Ensa and ARPP19. Both Greatwall and Ensa/ARPP19 are regulated by phosphorylation, but the dynamic regulation of Greatwall activit...
Autores principales: | Hégarat, Nadia, Vesely, Clare, Vinod, P. K., Ocasio, Cory, Peter, Nisha, Gannon, Julian, Oliver, Antony W., Novák, Béla, Hochegger, Helfrid |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879168/ https://www.ncbi.nlm.nih.gov/pubmed/24391510 http://dx.doi.org/10.1371/journal.pgen.1004004 |
Ejemplares similares
-
Correction: PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit
Publicado: (2014) -
The BEG (PP2A-B55/ENSA/Greatwall) Pathway Ensures Cytokinesis follows Chromosome Separation
por: Cundell, Michael J., et al.
Publicado: (2013) -
Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression
por: Della Monica, Rosa, et al.
Publicado: (2015) -
Fcp1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit
por: Visconti, Roberta, et al.
Publicado: (2012) -
Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B
por: Hégarat, Nadia, et al.
Publicado: (2020)