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DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4(+) T-Cell Population Structure

Altered DNA methylation patterns in CD4(+) T-cells indicate the importance of epigenetic mechanisms in inflammatory diseases. However, the identification of these alterations is complicated by the heterogeneity of most inflammatory diseases. Seasonal allergic rhinitis (SAR) is an optimal disease mod...

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Detalles Bibliográficos
Autores principales:	Nestor, Colm E., Barrenäs, Fredrik, Wang, Hui, Lentini, Antonio, Zhang, Huan, Bruhn, Sören, Jörnsten, Rebecka, Langston, Michael A., Rogers, Gary, Gustafsson, Mika, Benson, Mikael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879208/ https://www.ncbi.nlm.nih.gov/pubmed/24391521 http://dx.doi.org/10.1371/journal.pgen.1004059

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