Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism

Drug resistant strains of the malaria parasite, Plasmodium falciparum, have rendered chloroquine ineffective throughout much of the world. In parts of Africa and Asia, the coordinated shift from chloroquine to other drugs has resulted in the near disappearance of chloroquine-resistant (CQR) parasite...

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Detalles Bibliográficos
Autores principales: Lewis, Ian A., Wacker, Mark, Olszewski, Kellen L., Cobbold, Simon A., Baska, Katelynn S., Tan, Asako, Ferdig, Michael T., Llinás, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879234/
https://www.ncbi.nlm.nih.gov/pubmed/24391526
http://dx.doi.org/10.1371/journal.pgen.1004085

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