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Top3α Is Required during the Convergent Migration Step of Double Holliday Junction Dissolution

Although Blm and Top3α are known to form a minimal dissolvasome that can uniquely undo a double Holliday junction structure, the details of the mechanism remain unknown. It was originally suggested that Blm acts first to create a hemicatenane structure from branch migration of the junctions, followe...

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Detalles Bibliográficos
Autores principales: Chen, Stefanie Hartman, Plank, Jody L., Willcox, Smaranda, Griffith, Jack D., Hsieh, Tao-shih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879244/
https://www.ncbi.nlm.nih.gov/pubmed/24392087
http://dx.doi.org/10.1371/journal.pone.0083582