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Analysis of the Vaccine Potential of Plasmid DNA Encoding Nine Mycolactone Polyketide Synthase Domains in Mycobacterium ulcerans Infected Mice

There is no effective vaccine against Buruli ulcer. In experimental footpad infection of C57BL/6 mice with M. ulcerans, a prime-boost vaccination protocol using plasmid DNA encoding mycolyltransferase Ag85A of M. ulcerans and a homologous protein boost has shown significant, albeit transient protect...

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Detalles Bibliográficos
Autores principales:	Roupie, Virginie, Pidot, Sacha J., Einarsdottir, Tobba, Van Den Poel, Christophe, Jurion, Fabienne, Stinear, Timothy P., Huygen, Kris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879250/ https://www.ncbi.nlm.nih.gov/pubmed/24392169 http://dx.doi.org/10.1371/journal.pntd.0002604

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