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Accelerated Detection of Mycolactone Production and Response to Antibiotic Treatment in a Mouse Model of Mycobacterium ulcerans Disease

Diagnosis of the neglected tropical disease, Buruli ulcer, can be made by acid-fast smear microscopy, specimen culture on mycobacterial growth media, polymerase chain reaction (PCR), and/or histopathology. All have drawbacks, including non-specificity and requirements for prolonged culture at 32°C,...

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Detalles Bibliográficos
Autores principales:	Converse, Paul J., Xing, Yalan, Kim, Ki Hyun, Tyagi, Sandeep, Li, Si-Yang, Almeida, Deepak V., Nuermberger, Eric L., Grosset, Jacques H., Kishi, Yoshito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879254/ https://www.ncbi.nlm.nih.gov/pubmed/24392174 http://dx.doi.org/10.1371/journal.pntd.0002618

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