Antagonistic Interplay between Necdin and Bmi1 Controls Proliferation of Neural Precursor Cells in the Embryonic Mouse Neocortex

Neural precursor cells (NPCs) in the neocortex exhibit a high proliferation capacity during early embryonic development and give rise to cortical projection neurons after maturation. Necdin, a mammal-specific MAGE (melanoma antigen) family protein that possesses anti-mitotic and pro-survival activit...

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Detalles Bibliográficos
Autores principales: Minamide, Ryohei, Fujiwara, Kazushiro, Hasegawa, Koichi, Yoshikawa, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879318/
https://www.ncbi.nlm.nih.gov/pubmed/24392139
http://dx.doi.org/10.1371/journal.pone.0084460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879318/
https://www.ncbi.nlm.nih.gov/pubmed/24392139
http://dx.doi.org/10.1371/journal.pone.0084460

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