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The Small Fibrinopeptide Bβ(15–42) as Renoprotective Agent Preserving the Endothelial and Vascular Integrity in Early Ischemia Reperfusion Injury in the Mouse Kidney
Disruption of the renal endothelial integrity is pivotal for the development of a vascular leak, tissue edema and consequently acute kidney injury. Kidney ischemia amplifies endothelial activation and up-regulation of pro-inflammatory mechanisms. After restoring a sufficient blood flow, the kidney i...
Autores principales: | Urbschat, Anja, Zacharowski, Kai, Obermüller, Nicholas, Rupprecht, Katrin, Penzkofer, Daniela, Jennewein, Carla, Tran, Nguyen, Scheller, Bertram, Dimmeler, Stefanie, Paulus, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879329/ https://www.ncbi.nlm.nih.gov/pubmed/24392138 http://dx.doi.org/10.1371/journal.pone.0084432 |
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