Suppression of Interferon Lambda Signaling by SOCS-1 Results in Their Excessive Production during Influenza Virus Infection

Innate cytokine response provides the first line of defense against influenza virus infection. However, excessive production of cytokines appears to be critical in the pathogenesis of influenza virus. Interferon lambdas (IFN-λ) have been shown to be overproduced during influenza virus infection, but...

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Detalles Bibliográficos
Autores principales: Wei, Haitao, Wang, Song, Chen, Qinghuang, Chen, Yuhai, Chi, Xiaojuan, Zhang, Lianfeng, Huang, Shile, Gao, George F., Chen, Ji-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879354/
https://www.ncbi.nlm.nih.gov/pubmed/24391501
http://dx.doi.org/10.1371/journal.ppat.1003845

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