Control of mRNA stability contributes to low levels of nuclear poly(A) binding protein 1 (PABPN1) in skeletal muscle

BACKGROUND: The nuclear poly(A) binding protein 1 (PABPN1) is a ubiquitously expressed protein that plays critical roles at multiple steps in post-transcriptional regulation of gene expression. Short expansions of the polyalanine tract in the N-terminus of PABPN1 lead to oculopharyngeal muscular dys...

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Detalles Bibliográficos
Autores principales: Apponi, Luciano H, Corbett, Anita H, Pavlath, Grace K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879409/
https://www.ncbi.nlm.nih.gov/pubmed/24083404
http://dx.doi.org/10.1186/2044-5040-3-23

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