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Simulations of Enhancer Evolution Provide Mechanistic Insights into Gene Regulation

There is growing interest in models of regulatory sequence evolution. However, existing models specifically designed for regulatory sequences consider the independent evolution of individual transcription factor (TF)–binding sites, ignoring that the function and evolution of a binding site depends o...

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Detalles Bibliográficos
Autores principales:	Duque, Thyago, Samee, Md. Abul Hassan, Kazemian, Majid, Pham, Hannah N., Brodsky, Michael H., Sinha, Saurabh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879441/ https://www.ncbi.nlm.nih.gov/pubmed/24097306 http://dx.doi.org/10.1093/molbev/mst170

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