Genomic, RNAseq, and Molecular Modeling Evidence Suggests That the Major Allergen Domain in Insects Evolved from a Homodimeric Origin

The major allergen domain (MA) is widely distributed in insects. The crystal structure of a single Bla g 1 MA revealed a novel protein fold in which the fundamental structure was a duplex of two subsequences (monomers), which had diverged over time. This suggested that the evolutionary origin of the...

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Detalles Bibliográficos
Autores principales: Randall, Thomas A., Perera, Lalith, London, Robert E., Mueller, Geoffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879970/
https://www.ncbi.nlm.nih.gov/pubmed/24253356
http://dx.doi.org/10.1093/gbe/evt182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879970/
https://www.ncbi.nlm.nih.gov/pubmed/24253356
http://dx.doi.org/10.1093/gbe/evt182

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