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HIV-1-associated PKA acts as a cofactor for genome reverse transcription

BACKGROUND: Host cell proteins, including cellular kinases, are embarked into intact HIV-1 particles. We have previously shown that the Cα catalytic subunit of cAMP-dependent protein kinase is packaged within HIV-1 virions as an enzymatically active form able to phosphorylate a synthetic substrate i...

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Detalles Bibliográficos
Autores principales: Giroud, Charline, Chazal, Nathalie, Gay, Bernard, Eldin, Patrick, Brun, Sonia, Briant, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880072/
https://www.ncbi.nlm.nih.gov/pubmed/24344931
http://dx.doi.org/10.1186/1742-4690-10-157