Cargando…
Comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia
BACKGROUND: Remifentanil enhances intraoperative hemodynamic stability, suggesting that it may decrease intraoperative blood loss when included as an adjuvant to general anesthesia. This retrospective study compared intraoperative blood loss during spinal surgery in patients administered either remi...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880217/ https://www.ncbi.nlm.nih.gov/pubmed/24304964 http://dx.doi.org/10.1186/1471-2253-13-46 |
_version_ | 1782298052177952768 |
---|---|
author | Kawano, Hiroaki Manabe, Sawa Matsumoto, Tomomi Hamaguchi, Eisuke Kinoshita, Michiko Tada, Fumihiko Oshita, Shuzo |
author_facet | Kawano, Hiroaki Manabe, Sawa Matsumoto, Tomomi Hamaguchi, Eisuke Kinoshita, Michiko Tada, Fumihiko Oshita, Shuzo |
author_sort | Kawano, Hiroaki |
collection | PubMed |
description | BACKGROUND: Remifentanil enhances intraoperative hemodynamic stability, suggesting that it may decrease intraoperative blood loss when included as an adjuvant to general anesthesia. This retrospective study compared intraoperative blood loss during spinal surgery in patients administered either remifentanil or fentanyl as an opioid adjuvant. METHODS: We reviewed clinical and surgical data from 64 consecutive laminoplasty or laminectomy patients treated at National Hospital Organization Zentsuji Hospital between April 2010 and March 2011. Patients received either remifentanil (n = 35) or fentanyl (n = 29) as an opioid analgesic during general anesthesia. In addition to intraoperative blood loss, indices of hemodynamic stability, including heart rate as well as systolic, mean, and diastolic blood pressure (BP), were compared over the entire perioperative period between remifentanil and fentanyl groups. RESULTS: The remifentanil group exhibited significantly lower intraoperative arterial BP than the fentanyl group. Intraoperative blood loss was also significantly lower in the remifentanil group (125 ± 67 mL vs. 165 ± 82 mL, P = 0.035). CONCLUSIONS: Intraoperative blood loss during spinal surgery was decreased in patients who received remifentanil as an opioid adjuvant, possibly because of lower intraoperative BP. A larger-scale prospective randomized controlled trial is warranted to confirm our results and to test whether remifentanil can decrease intraoperative blood loss during other surgical procedures. |
format | Online Article Text |
id | pubmed-3880217 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-38802172014-01-04 Comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia Kawano, Hiroaki Manabe, Sawa Matsumoto, Tomomi Hamaguchi, Eisuke Kinoshita, Michiko Tada, Fumihiko Oshita, Shuzo BMC Anesthesiol Research Article BACKGROUND: Remifentanil enhances intraoperative hemodynamic stability, suggesting that it may decrease intraoperative blood loss when included as an adjuvant to general anesthesia. This retrospective study compared intraoperative blood loss during spinal surgery in patients administered either remifentanil or fentanyl as an opioid adjuvant. METHODS: We reviewed clinical and surgical data from 64 consecutive laminoplasty or laminectomy patients treated at National Hospital Organization Zentsuji Hospital between April 2010 and March 2011. Patients received either remifentanil (n = 35) or fentanyl (n = 29) as an opioid analgesic during general anesthesia. In addition to intraoperative blood loss, indices of hemodynamic stability, including heart rate as well as systolic, mean, and diastolic blood pressure (BP), were compared over the entire perioperative period between remifentanil and fentanyl groups. RESULTS: The remifentanil group exhibited significantly lower intraoperative arterial BP than the fentanyl group. Intraoperative blood loss was also significantly lower in the remifentanil group (125 ± 67 mL vs. 165 ± 82 mL, P = 0.035). CONCLUSIONS: Intraoperative blood loss during spinal surgery was decreased in patients who received remifentanil as an opioid adjuvant, possibly because of lower intraoperative BP. A larger-scale prospective randomized controlled trial is warranted to confirm our results and to test whether remifentanil can decrease intraoperative blood loss during other surgical procedures. BioMed Central 2013-12-05 /pmc/articles/PMC3880217/ /pubmed/24304964 http://dx.doi.org/10.1186/1471-2253-13-46 Text en Copyright © 2013 Kawano et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Kawano, Hiroaki Manabe, Sawa Matsumoto, Tomomi Hamaguchi, Eisuke Kinoshita, Michiko Tada, Fumihiko Oshita, Shuzo Comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia |
title | Comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia |
title_full | Comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia |
title_fullStr | Comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia |
title_full_unstemmed | Comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia |
title_short | Comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia |
title_sort | comparison of intraoperative blood loss during spinal surgery using either remifentanil or fentanyl as an adjuvant to general anesthesia |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880217/ https://www.ncbi.nlm.nih.gov/pubmed/24304964 http://dx.doi.org/10.1186/1471-2253-13-46 |
work_keys_str_mv | AT kawanohiroaki comparisonofintraoperativebloodlossduringspinalsurgeryusingeitherremifentanilorfentanylasanadjuvanttogeneralanesthesia AT manabesawa comparisonofintraoperativebloodlossduringspinalsurgeryusingeitherremifentanilorfentanylasanadjuvanttogeneralanesthesia AT matsumototomomi comparisonofintraoperativebloodlossduringspinalsurgeryusingeitherremifentanilorfentanylasanadjuvanttogeneralanesthesia AT hamaguchieisuke comparisonofintraoperativebloodlossduringspinalsurgeryusingeitherremifentanilorfentanylasanadjuvanttogeneralanesthesia AT kinoshitamichiko comparisonofintraoperativebloodlossduringspinalsurgeryusingeitherremifentanilorfentanylasanadjuvanttogeneralanesthesia AT tadafumihiko comparisonofintraoperativebloodlossduringspinalsurgeryusingeitherremifentanilorfentanylasanadjuvanttogeneralanesthesia AT oshitashuzo comparisonofintraoperativebloodlossduringspinalsurgeryusingeitherremifentanilorfentanylasanadjuvanttogeneralanesthesia |