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A Dual TLR Agonist Adjuvant Enhances the Immunogenicity and Protective Efficacy of the Tuberculosis Vaccine Antigen ID93
With over eight million cases of tuberculosis each year there is a pressing need for the development of new vaccines against Mycobacterium tuberculosis. Subunit vaccines consisting of recombinant proteins are an attractive vaccine approach due to their inherent safety compared to attenuated live vac...
Autores principales: | Orr, Mark T., Beebe, Elyse A., Hudson, Thomas E., Moon, James J., Fox, Christopher B., Reed, Steven G., Coler, Rhea N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880254/ https://www.ncbi.nlm.nih.gov/pubmed/24404140 http://dx.doi.org/10.1371/journal.pone.0083884 |
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