Role of SOX2 in the Etiology of Embryonal Carcinoma, Based on Analysis of the NCCIT and NT2 Cell Lines

The transcription factor SOX2, associated with amongst others OCT3/4, is essential for maintenance of pluripotency and self-renewal of embryonic stem cells. SOX2 is highly expressed in embryonal carcinoma (EC), the stem cell component of malignant nonseminomatous germ cell tumors, referred to as ger...

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Detalles Bibliográficos
Autores principales: Eini, Ronak, Stoop, Hans, Gillis, Ad J. M., Biermann, Katharina, Dorssers, Lambert C. J., Looijenga, Leendert H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880257/
https://www.ncbi.nlm.nih.gov/pubmed/24404135
http://dx.doi.org/10.1371/journal.pone.0083585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880257/
https://www.ncbi.nlm.nih.gov/pubmed/24404135
http://dx.doi.org/10.1371/journal.pone.0083585

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