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Rational Design of a New Trypanosoma rangeli Trans-Sialidase for Efficient Sialylation of Glycans

This paper reports rational engineering of Trypanosoma rangeli sialidase to develop an effective enzyme for a potentially important type of reactivity: production of sialylated prebiotic glycans. The Trypanosoma cruzi trans-sialidase and the homologous T. rangeli sialidase has previously been used t...

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Detalles Bibliográficos
Autores principales:	Jers, Carsten, Michalak, Malwina, Larsen, Dorte M., Kepp, Kasper P., Li, Haiying, Guo, Yao, Kirpekar, Finn, Meyer, Anne S., Mikkelsen, Jørn D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880268/ https://www.ncbi.nlm.nih.gov/pubmed/24404142 http://dx.doi.org/10.1371/journal.pone.0083902

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