STAT3 Oligonucleotide Inhibits Tumor Angiogenesis in Preclinical Models of Squamous Cell Carcinoma

PURPOSE: Signal transducer and activator of transcription 3 (STAT3) has shown to play a critical role in head and neck squamous cell carcinoma (HNSCC) and we have recently completed clinical trials of STAT3 decoy oligonucleotide in patients with recurrent or metastatic HNSCC. However, there is limit...

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Detalles Bibliográficos
Autores principales: Klein, Jonah D., Sano, Daisuke, Sen, Malabika, Myers, Jeffrey N., Grandis, Jennifer R., Kim, Seungwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880270/
https://www.ncbi.nlm.nih.gov/pubmed/24404126
http://dx.doi.org/10.1371/journal.pone.0081819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880270/
https://www.ncbi.nlm.nih.gov/pubmed/24404126
http://dx.doi.org/10.1371/journal.pone.0081819

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